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Hiroto Iinuma Selected Research

Oxolinic Acid

1/2021A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke.
10/2019Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay.

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Hiroto Iinuma Research Topics

Disease

2Malignant Hyperthermia
01/2021 - 10/2019
1Contracture
01/2021
1Heat Stroke (Heatstroke)
01/2021
1Central Core Myopathy (Central Core Disease)
10/2019

Drug/Important Bio-Agent (IBA)

2Oxolinic AcidIBA
01/2021 - 10/2019
2Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA
01/2021 - 10/2019
1CationsIBA
01/2021
1Halothane (Fluothane)FDA Link
01/2021
1IsofluraneFDA LinkGeneric
01/2021
1AcidsIBA
01/2021
1Caffeine (No Doz)FDA LinkGeneric
01/2021
1CalciumIBA
10/2019

Therapy/Procedure

1Anesthesia
01/2021